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Ac2O-Mediated Dearylacetylative Dimerization of 2‑Arylacetyl-1-naphthols: Synthesis of Naphtho[1,2‑b]furan-3-ones

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Figshare2020-01-16 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Ac_sub_2_sub_O-Mediated_Dearylacetylative_Dimerization_of_2_Arylacetyl-1-naphthols_Synthesis_of_Naphtho_1_2_i_b_i_furan-3-ones/11708505
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资源简介:
A novel and efficient route for the synthesis of 2-aryl-2-naphthyl naphtho­[1,2-b]­furan-3-ones is described via NaH/Ac2O-mediated dearylacetylative dimerization of 2-arylacetyl-1-naphthols in refluxing THF under open-flask conditions. A plausible mechanism is also proposed and discussed. Various reaction conditions are investigated for one-pot transformation.
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2020-01-16
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