Relationship Between Real World Evidence Publications and Entresto Sales

This dataset assesses the relationship between the cadence of RWE publications and sales of sacubitril/valsartan (Entresto®) following launch. The data reveal that an additional RWE-related publication was associated with an estimated mean increase in quarterly sales of $1.8M (from quarter q to q+1 following publication), $3.5M (from q+1 to q+2), and $2.7M (from q+2 to q+3). In adjusted models, an additional RWE publication was associated with a mean gain in sales from quarter q+1 to q+2 of $2.6M. RWE publications were not associated with an increase in sales in the quarter following publication, and the association was attenuated by third quarter following publication.

本数据集旨在评估真实世界证据（RWE）出版物频率与上市后沙库巴曲缬沙坦/缬沙坦（Entresto®）销售量之间的关系。数据显示，每增加一份RWE相关出版物，季度销售量平均增长约180万美元（自发布季度q至发布后q+1季度），350万美元（自q+1季度至q+2季度），以及270万美元（自q+2季度至q+3季度）。在调整后的模型中，每增加一份RWE出版物，q+1季度至q+2季度的平均销售额增长约为260万美元。RWE出版物与发布后季度的销售额增长无显著关联，且这种关联在发布后的第三季度逐渐减弱。