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Experimentally validated peptide inhibitors of E proteins.

NIAID Data Ecosystem2026-03-09 收录

蛋白质抑制剂

肿瘤药物靶点验证

数据链接：

https://figshare.com/articles/dataset/Experimentally_validated_peptide_inhibitors_of_E_proteins_/2578552 数据链接链接失效反馈

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资源简介：

Experimentally validated peptide inhibitors of E proteins.

应用场景：

创建时间：

2016-02-22

神经退行性疾病模型

肿瘤药物靶点验证

Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the com

NIAID Data Ecosystem100

BindingDB Entry 50018569: Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation.

肿瘤药物靶点验证

抑制剂筛选

Small molecule binding data for protein CTP synthase 1 and CTP synthase 2, Uniprot P17812, P70303, P70698, Q5U2N0, and Q9NRF8

DataCite Commons2024-04-26 更新90

Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors

药物设计

蛋白质抑制剂

The FK506-binding protein 51 (FKBP51) emerged as a key player in several diseases like stress-related disorders, chronic pain, and obesity. Linear analogues of FK506 called SAFit were shown to be high

Figshare2021-03-05 更新20

BindingDB Entry 50011894: Cholesteryl ester transfer protein (CETP) inhibitors based on cyclic urea, bicyclic urea and bicyclic sulfamide cores.

药物设计

蛋白质抑制剂

Small molecule binding data for protein Cholesteryl ester transfer protein, Uniprot P11597

Mendeley Data2024-03-27 更新100

Thermal Shift Assay Data

蛋白质稳定性

肿瘤药物靶点验证

https://pubmed.ncbi.nlm.nih.gov/33479120/

Figshare2024-05-20 更新30