Transcriptomics profiling of white adipose tissue of wildtype (WT) mice fed a normal chow diet (NCD) or high-fat diet (HFD)

Adipose tissue is a crucial metabolic organ maintaining energy homeostasis via catabolic and anabolic metabolism. As high-fat diet feeding leads to metabolic dysfunction, here, we aimed to study the effect of 8 weeks of high-fat diet feeding on WT mice and compare genes differentially regulated depending on the type of diets intaking. White adipose tissue mRNA profiles of WT mice fed a NCD or HFD were generated by deep sequencing. Three biological replicates were analyzed for each of two conditions.