A Formal Synthesis of (±)-Arborisidine
收藏NIAID Data Ecosystem2026-05-01 收录
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https://figshare.com/articles/dataset/A_Formal_Synthesis_of_-Arborisidine/25702426
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资源简介：
Herein, we report a formal synthesis of (±)-arborisidine
via
the creation of Jiao’s intermediate with the critical caged
structure. Starting from tryptamine, a Pictet–Spengler cyclization
forged the piperidine ring, a Pd-catalyzed indole allylation and ring-closing
metathesis protocol afforded a bridged aza-bicyclo[3.3.1]nonane moiety,
and an intramolecular N-alkylation closed the final pyrrolidine ring.
This study provides a new approach to the unique caged framework of
arborisidine and relevant alkaloids.
创建时间：
2024-04-26
