Gene expression profile at single cell level of cells from the murine small intestine (SI) lacking functional Apc.. Gene expression profile at single cell level of cells from the murine small intestine (SI) lacking functional Apc.

We used single cell RNA sequencing (scRNA-seq) to analyze the diversity of cells within the murine small intestine in the absence of functional Apc. Overall design: Cells from a 5-15cm portion of small intestine were isolated from mice with short term Apc inactivation, before analysis with scRNAseq