Gene expression analysis in canine discoid/chronic lupus erythematosus, mucocutaneous lupus erythematosus and pyoderma

We performed a comparative immunology case study of client-owned dogs to determine if immune and skin gene expression profiles in spontaneous canine cutaneous lupus erythematosus mirror those observed in human cutaneous lupus. Gene expression was analyzed using 160 custom Nanostring probes to analyze 7 canines with DLE, 1 canine with CCLE, 1 canine with MLE and 1 canine with pyoderma compared to 5 healthy controls (leg margin excisions). UPDATE: [09-11-2024] For Sample GSM4869949, the title was changed from "Skin_biopsy_DICLE_case1" to "Skin_biopsy_Control/Pyoderma_case3", and the disease status was changed from "DICLE" to "Control/Pyoderma".