Interventions: On Day 1, patients treated with FOLFIRI therapy received a 2-hour intravenous infusion of CPT-11 (150 mg/m2) combined with 1-LV (200 mg/m2), followed by a rapid intravenous infusion of
We sought to compare melanomas diagnosed immediately following the reopening after lockdown (put in place to halt the spread of COVID-19) to those diagnosed during the same months in the 5 preceding y
Raw dataset for a prospective, randomised, open-label study comparing short-course radiotherapy with consolidation chemotherapy versus conventionally fractionated long-course chemoradiotherapy for the
As FDA-approved chemotherapeutic agents, cisplatin, oxaliplatin, and 5-fluorouracil are widely used in clinic but limited by severe side-effects. To ameliorate their respective defects, a series of “d
The Traf2- and Nck-interacting protein kinase (TNIK) is a downstream signal protein of the Wnt/β-catenin pathway and has been thought of as a potential target for the treatment of colorectal cancer (C
