A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells
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https://osdr.nasa.gov/bio/repo/data/studies/OSD-91
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资源简介:
Here, in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6 lymphoblastoid cells upon exposure to micro-gravity conditions. The results reported here indicate that simulated microgravity alters methylation patterns in a limited way and subsequently the expression of genes involved in stress response like ATF3, FBXO17, MAP3K13 and VCL in TK6 cells. Overall design: Examination of RNA-seq with 2 replicates each for 1 cell type
提供机构:
NASA GeneLab
创建时间:
2020-08-19



