Data extraction table for "Health effects of drinking 100% fruit and/or vegetable juice: An umbrella review of systematic reviews and meta-analyses"

The full data extraction table for "Health effects of drinking 100% fruit and/or vegetable juice: An umbrella review of systematic reviews and meta-analyses" - registered as "What are the effects of 100% fruit and/or vegetable juice consumption, as compared to placebo or low intakes, on human health outcomes relevant to population health?" PROSPERO 2022 CRD42022380588 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022380588

We conducted an umbrella review of systematic literature reviews (SLRs) with meta-analyses (MAs) to summarise the health benefits of drinking 100% fruit and/or vegetable juice. Four electronic databases will be searched from inception with no date limits: MEDLINE (via PubMed), The Cochrane Library (Reviews and CENTRAL), EMBASE, and CINAHL (via EBSCO). The systematic search strategy was designed to include a combination of both controlled vocabulary (MeSH terms and publication type) and keywords (by title and abstract). The keywords repeated the controlled vocabulary terms plus keywords specific to the topic. The search strategy was designed in PubMed and then translated to the other databases. Types of study to be included Systematic literature reviews with meta-analysis.Exclusions: Systematic literature reviews with no meta-analysis, cross-sectional studies, single arm interventions, narrative reviews, expert opinion articles, or consensus guidelines.

Screening, quality, risk of bias and content overlap tools were applied, and extracted data are tabulated (tab 1), GRADE applied (tab 2) and ROBIS applied (tab 3).

Data represent almost 2 million subject data points. Of the primary MAs 10 MAs reported health benefits (blood pressure, vascular function, inflammation, stroke mortality), three MAs reported adverse risks (CVD mortality, prostate cancer, type 2 diabetes risk), while most reported no effect (blood lipids, body composition, liver function, metabolic health, cancers, and inflammation).

Findings confirm there are health benefits associated with 100% juice consumption, with limited harms identified at this level of evidence. The balance of evidence continues to support the inclusion of 100% juice as a core food in dietary guidelines.