10 Synthetic Genomics Datasets

These are 10 synthetic genomics datasets generated with NEAT v3 (based on TP53 gene of Homo Sapiens) for the use case of benchmarking somatic variant callers. To find more about our generating framework please visit synth4bench GitHub repository. The datasets explore intrinsic NGS data parameters for the use case of observing their effect on tumor-only somatic variant calling algorithms. From the 10 datasets, there are 5 of them with different coverage (while keeping all other parameters fixed) and 5 with varying read length. The reads in all datasets are paired-end . Name of File Coverage Lenght of Reads 300_30_10 300x 150 700_70_10 700x 150 1000_100_10 1000x 150 3000_300_10 3000x 150 5000_500_10 5000x 150 1000_50 1000x 50 1000_100 1000x 100 1000_170 1000x 170 1000_200 1000x 200 1000_300 1000x 300