A Basophil-Fibroblast Pro-inflammatory Axis Fuels Type 2 Skin Inflammation
收藏NIAID Data Ecosystem2026-05-02 收录
官方服务：
资源简介：
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景：
创建时间：
2025-08-05
相关数据集
Production of Superoxide Anions by Keratinocytes Initiates P. acnes -Induced Inflammation of the Skin
Acne vulgaris is a chronic inflammatory disorder of the sebaceous follicles. Propionibacterium acnes (P. acnes), a gram-positive anareobic bacterium, plays a critical role in the development of these
NIAID Data Ecosystem60
TIMP3, a CLOCK-controlled gene, determines cell susceptibility to UV-induced expression of inflammatory factors in human keratinocytes.
To search for CLOCK-controlled genes in human keratinocytes, we introduced siRNAs against CLOCK and harvested the cells at two time points, ZT 32 and 44. We speculated that those genes that were downr
NIAID Data Ecosystem30
mRNA sequencing of skins isolated from B6;129S4-Npytm2Rpa/J homozygous mice and wildtype litter mates reveals transcriptomic changes indicative of skin inflammation associated with Npy overexpression.
Neuropeptide Y (NPY) is a pleiotropic peptide produced in the central nervous system and peripheral organs. Despite conjectures that NPY may have a role in skin physiology and pathology, the effects o
NIAID Data Ecosystem10
Comparing transcriptional profiles of skin biopsies from healthy controls and subjects with chronic pruritus of unknown origin and atopic dermatitis
Type 2 inflammation contributes to the pathology of pruritic skin diseases such as atopic dermatitis (AD). Chronic pruritus of unknown origin (CPUO) is a skin condition of unknown etiology that typica
NIAID Data Ecosystem40
DataSheet_1_A Murine Point Mutation of Sgpl1 Skin Is Enriched With Vγ6 IL17-Producing Cell and Revealed With Hyperpigmentation After Imiquimod Treatment.csv
Sphingosine-1-phosphate lyase is encoded by the Sgpl1 gene, degrades S1P, and is crucial for S1P homeostasis in animal models and humans. S1P lyase deficient patients suffer from adrenal insufficiency
NIAID Data Ecosystem10
