Human SIRT2 in Complex with RW-78
收藏Protein Data Bank Japan2025-11-26 更新2026-05-24 收录
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https://pdbj.org/mine/summary/9s46
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Human SIRT2 in Complex with RW-78 Descriptor: 1,2-ETHANEDIOL, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ... Authors: Wirawan, R, Frei, M, Heider, A, Papenkordt, N, Friedrich, F, Wein, T, Jung, M, Groll, M, Huber, E.M, Bracher, F. Deposit date: 2025-07-25 Release date: 2025-08-20 Last modified: 2025-11-26 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD + co-factor binding. Rsc Med Chem, 16, 2025
创建时间：
2025-07-25
