Significantly associated SNPs in the GWAS for WBC subtypes.

aSNPs that satisfied genome-wide significance threshold of P<5.0×10−8 in the combined study in Japanese population were indicated.
bThe allele that increased the count of the corresponding WBC subtype was denoted as effect allele (EA) and is indicated based on the forward strand.
cFrequency of allele 1.
dImputation score of Rsq by MACH 1.0 [26]. For the genotyped SNP, “-” is indicated.
eEffect size of effect allele on the normalized trait.
fEffect size of effect allele on the transformed trait. Details of the study by the CHARGE Consortium is summarized in Table S5 and described elsewhere [23].
GWAS, Genome-wide association study; WBC, white blood cell; EA, effect allele; SE, standard error.