Tumor-to-organ ratios.

Tumor-to-organ ratios were calculated from the organ distribution of 131I-CaIX-P1 in female Balb/c nu/nu mice carrying SKRC 52 tumors after 15 min (n = 8 animals), 60 min (n = 10 animals) and 240 min (n = 3 animals) circulation of the radioligand in the blood stream. For in vivo blocking, 100 µL unlabeled peptide at a concentration of 10−3 M was co-injected with the radioligand and tumor-to-organ ratios were calculated after 15 min (n = 3 animals) and 60 min (n = 3 animals) circulation in the blood stream.