Plasma was obtained from 13 donors, 12 of which had been previously vaccinated within the past 5 years with trivalent or quadrivalent seasonal influenza vaccines. Plasma baseline anti-influenza IgG wa
*Mean and percentiles 25%–75%. **Not all subjects returned for 9- and 12-months follow-up visits. Carbon monoxide concentration expressed in ppm. High = Subgroup of subjects with high anti-nicotine an
Human antibody response studies are largely restricted to periods of high immune activity (e.g., vaccination). To comprehensively understand the healthy B cell immune repertoire and how this changes o
Glycosylation plays a critical role in the bioactivity of proteins. For example, glycosylation of the SARS-CoV-2 Spike receptor-binding domain affects viral entry into host cells. Similarly, the glyco