A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging
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https://www.ncbi.nlm.nih.gov/sra/SRP032942
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资源简介:
Our data throw light upon the effect of WRN deficiency on gene expression and epigenomic modification, which indicates aging-associated changes from both genomic and epigenomic level. Overall design: It was compared between WRN+/+ and WRN-/- in hESCs and hMSCs that the gene expression landscapes and epigenetic modifications(H3K4me3, H3K27me3, H3K9me3 and 5-methylcytosine).
创建时间:
2017-09-17



