Statins, a class of drugs that can effectively remove cholesterol from serum, are used to regulate plasma total cholesterol and reduce the risk of cardiovascular diseases, but it is still unclear whet
Data of Figure S4, “The ratio of ursodeoxycholyltaurine to 7-oxolithocholyltaurine serves as a biomarker of decreased 11β-hydroxysteroid dehydrogenase 1 activity in mouse” The Dataset (doi:10.1111/b
Amplicon sequencing was used to characterise the dose-dependent impact of methotrexate treatment on the faecal microbial profile of rats. In parallel, untargeted and targeted UPLC-MS approaches were p
Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics
