RNase H dependent Antisense oligonucleotides in the nucleus causes transcription termination
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133374
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资源简介：
The aim of this study is to characterize Rnase H ASO mediated transcription events on chromatin. chromatin associated RNA sequencing (chrRNA-seq): chromatin fraction were isolated from MHT cells after 24 hrs ASO free uptake. 14 different gapmer ASOs treatments targeting on 2 genes and 6 different controls were conducted for sequencing. Precision nuclear run-on sequencing (PRO-seq): biotin labelled substrates were applied after ASO treatments. 6 different ASO treatments and 3 controls were applied for PRO-seq.
创建时间：
2019-10-02
