Total Synthesis of Integrastatin B Enabled by a Benzofuran Oxidative Dearomatization Cascade
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https://figshare.com/articles/dataset/Total_Synthesis_of_Integrastatin_B_Enabled_by_a_Benzofuran_Oxidative_Dearomatization_Cascade/3085351
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资源简介：
The
first total synthesis of integrastatin B, a potent HIV-1 integrase
inhibitor, has been accomplished in seven steps with a 17.9% overall
yield employing easily accessible starting compounds. The Oxone-mediated
oxidative benzofuran dearomatization cascade has been employed as
the key skeletal construct to forge the central tetracyclic nucleus.
创建时间：
2016-03-14
