Additional file 8: Table S7. of Machine learning classifier for identification of damaging missense mutations exclusive to human mitochondrial DNA-encoded polypeptides

Conservation Index (CI) in Eukaryota. Each score is described by its gene (GENE), amino acid position within the polypeptide (AA position) and wild type amino acid (WT AA) as well as number of ortholog sequences used in the multiple sequence alignment (Sequences). CI is described as a percentage. The revised Cambridge reference sequence (rCRS, NC_012920.1) was used to define the reference amino acid sequence of each gene. (XLS 453 kb)