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Genome-wide identification of SCL/Tal1s functional targets; insights into its mechanisms of action in primary erythroid cells

ChEBI2010-05-27 更新2026-07-21 收录

基因功能靶点识别

细胞分化机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-21877 数据链接链接失效反馈

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Genome-wide identification of SCL/Tal1s functional targets; insights into its mechanisms of action in primary erythroid cells

应用场景：

创建时间：

2010-05-27

细胞分化机制

抗体亲和力成熟

Long-lived plasma cells (PCs) secrete antibodies that can provide sustained immunity against infection. It has been proposed that high affinity cells are preferentially selected into this compartment,

NIAID Data Ecosystem60

FTH1P3, a Novel H-Ferritin Pseudogene Transcriptionally Active, Is Ubiquitously Expressed and Regulated during Cell Differentiation

基因转录调控

细胞分化机制

Ferritin, the major iron storage protein, performs its essential functions in the cytoplasm, nucleus and mitochondria. The variable assembly of 24 subunits of the Heavy (H) and Light (L) type composes

NIAID Data Ecosystem40

Selective gene expression maintains human tRNA anticodon pools during differentiation. Selective gene expression maintains human tRNA anticodon pools during differentiation

tRNA表达调控

细胞分化机制

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem30

Tbet regulates the accessible chromatin of Be1 B cells. Tbet regulates the accessible chromatin of Be1 B cells

细胞分化机制

染色质可及性分析

To investigate the role of Tbet in B cell differentiation to "effector-like" antibody secreting cells (ASC's) we utilized an ex vivo culture system to differentiate B cells in the presence of Th1 (Be1

NIAID Data Ecosystem60

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4 (ChIP-seq)

细胞分化机制

ChIP-seq分析

Temporal analysis of Irf4 and PU.1 genome binding during B cell activation and differentiation in vitro using antigen (NP-Ficoll) CD40L and IL-2/4/5 cytokines (see Molecular Systems Biology 7:495 for

NIAID Data Ecosystem40

Genome-wide identification of SCL/Tal1s functional targets; insights into its mechanisms of action in primary erythroid cells

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相关数据集

Genome-wide identification of SCL/Tal1s functional targets; insights into its mechanisms of action in primary erythroid cells