Additional file 1 of Radiation-response in primary fibroblasts of long-term survivors of childhood cancer with and without second primary neoplasms: the KiKme study

Additional file 1. All results of the differential gene expression analyses. AF1a. Complete list of differentially expressed genes. Model 1 considers age at sampling and sex; model 2 considers age at sampling, sex, age at and year of first diagnosis, and tumor type (not used with data from cancer-free controls). Abbreviations: Gy = Gray, N0 = fibroblasts of cancer-free controls, N1 = fibroblasts of childhood-cancer survivors, N2+  = fibroblasts of childhood-cancer survivors with at least one second primary neoplasm, FDR = p-value adjusted for false discovery rate. AF1b. Differential expression computed with the interaction of radiation and donor group. The comparison-column refers to the donor groups that were compared in the analysis for interactions of the effect of radiation dose and donor group to identify genes showing a differential reaction to radiation exposure between donor groups. Abbreviations: Gy = Gray, N0 = fibroblasts of cancer-free controls, N1 = fibroblasts of childhood-cancer survivors, N2+  = fibroblasts of childhood-cancer survivors with at least one second primary neoplasm, FDR = p-value adjusted for false discovery rate.