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Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3543105A

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Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3543105A Descriptor: (2S)-2-({3,5-dicyano-4-ethyl-6-[4-(2-hydroxyethyl)-1,4-diazepan-1-yl]pyridin-2-yl}sulfanyl)-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (12-MER), ... Authors: Horton, J.R, Pathuri, S, Cheng, X. Deposit date: 2021-10-03 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
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2021-10-03
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