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Mitochondrial Ribosome profiling RNASeq data from mtIF2 and mtIF3 knock-out HEK cells versus wildtype
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2020-08-25
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Calculations related to figures Figs 5E and S9.
Determination of the peak area and error bar calculation. From the UV absorption profile of each gradient, areas under each peak corresponding to ribosomal subunits or 80S ribosomes were measured. To
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Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 3]. Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 3]
Stop codon readthrough (SCR) occurs when the ribosome miscodes at a stop codon. Such readthrough events can be therapeutically desirable when a premature termination codon (PTC) is found in a critical
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Study of ribosome dynamics after eIF5A depletion in budding yeast
eIF5A is an essential translation elongation factor present in all eukaryotes, and the only known protein to follow a post-translational modification called hypusination. Here, we performed a wide ana
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Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice
In the present work we have applied analytical methods to map repair events in rDNA using data generated by the newly developed XR-seq genome-wide single nucleotide repair technology. We find that in
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Genome-wide translational changes induced by the prion [PSI+]
Prions are infectious proteins that can adopt a structural conformation different from that of the normal protein. This change of conformation is then propagated among other molecules of the same prot
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