Identification of orthologs of CPAP1 and CPAP3 proteins in phyla Arthropoda and Nematoda.

Representative members for different insect orders, sub-phyla and phyla: Diptera- Drosophila, Culex, Anopheles, Aedes, Glossina, Saptomyza, Lutzomiya, Culicoides; Lepidoptera- Choristeneura, Bombyx, Spodoptera, Loxostege, Tenebrio, Mamestra, Helicoverpa, Heliconius, Plutella; Coleoptera- Tribolium, Holotrichia, Popillia, Tenebrio; Hymenoptera- Harpegnathus, Nasonia, Solenopsis, Apis, Acromyrmex, Bombus, Camponotus; Hemiptera- Acyrthosiphon; Phthiraptera- Pediculus; Crustacea- Daphnia, Artemia, Lepeophtheirus, Caligus, Rimicaris; Chelicerata- Ixodes; Nematoda- Ascaris, Caenorhabditis. id: insufficient data; “+”if overall similarity had e-values greater than >e−22; “−”if overall similarity had e-values less than −22. “*”In Nematoda indicates the presence of putative homologs of CPAP proteins in C. elegans and Brugia malayi. The Brugia malayi protein XP_001900473 has three ChtBD2’s but it is more closely related to the peritrophic matrix protein consensus of the ChtBD2 families [6]. Another C. elegans protein CEJ-1 with 3 ChtBD2 has interspersed mucin domains. However, their orthology to the CPAP3 family proteins is undetermined.