ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma
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https://data.mendeley.com/datasets/2bhw7wng2j
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资源简介：
Highlights
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Loss of p62 in the stroma reprograms metabolism to endure glutamine deprivation
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Stromal loss of p62 upregulates ATF4 to sustain asparagine-mediated tumor growth
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p62 regulates ATF4 stability through ubiquitin-mediated proteasomal degradation
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Fibroblast-selective deletion of p62 activates the ATF4-ASNS axis in vivo
创建时间：
2018-01-24
