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MERVL/Zscan4 network activation results in transient genome-wide DNA demethylation of mESCs

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NIAID Data Ecosystem2026-05-01 收录
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Several previous studies have noted a rare sub-population of murine Embryonic Stem Cells (mESCs) which seem to express genes otherwise specific to the 2-cell stage of embryonic development. Here we sorted single cells from a MERVL/Zscan4 reporter line to investigate the continuum of expression as cells go from the standard state to this 2C-like state.

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2023-10-13
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