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Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner [1]. Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner [1]

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NIAID Data Ecosystem2026-03-13 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA869560
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资源简介:
Loss of SAMHD1 causes chronic activaiton of the MDA5/MAVS dsRNA sensing pathway, only when cGAS/STING signaling is intact. Overall design: Peritoneal macrophages from mutant and control mice were isolated by FACS. Total RNA was subjected to next generation mRNA sequencing.
创建时间:
2022-08-15
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