Level of expression of the different receptors targeted by sunitinib and sorafenib.

(−) indicates that no or very low levels of detectable amplified cDNA were observed on an agarose gel; (+) indicates amplified cDNA. The Score/8 indicates the presence of receptorsargeted by sunitinib or sorafenib. The E Score indicates the relative expression level as detected by quantitative and semi-quantitative PCR. A level of sensitivity to sunitinib similar to that of 786-O cells is indicated by a grey background; sensitivity only to higher concentrations of the drug is indicated by a black background.