Crystal structure of c-Met in complex with LY2801653
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Crystal structure of c-Met in complex with LY2801653 Descriptor: Hepatocyte growth factor receptor, N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide Authors: Wang, Y, Stout, S.L. Deposit date: 2012-03-28 Release date: 2013-04-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models. Invest New Drugs, 31, 2013
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2012-03-28
