Transcriptional profiling of intestinal changes following APC loss
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE112226
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Vil-CreERT2 was used to drive loss of APC (Adenomatous polyposis coli) in the murine intestinal epithelium. 4 days post induction, mice were sampled and 1cm of tissue from the proximal intestine was collected into RNA later. This was compared to control (wild-type) intestine. This analysis allows investigation of transcriptional changes following APC loss (and therefore activation of the WNT signalling pathway). RNAseq Expression data from whole intestine comparing WT intestine vs VilCreER APCfl/fl
创建时间:
2022-11-22



