IL1 Signaling
收藏NIAID Data Ecosystem2026-05-10 收录
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Interleukin-1 (IL-1) is a proinflammatory cytokine produced by activated macrophages, endothelial cells, B cells and fibroblasts. IL-1 play a central role in inflammation and host defence against infection. The signalling pathways involve two adapter proteins, MyD88 and Tollip, which via two IL-1 receptor-associated kinases (IRAK and IRAK-2) activate transcription factors such as nuclear factor-kappa B.
创建时间:
2025-11-26



