Crystal Structure of human Beta Secretase complexed with IXS
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Crystal Structure of human Beta Secretase complexed with IXS Descriptor: Beta-secretase 1, N-[(1S)-1-benzyl-2-{[(1S)-2-(isobutylamino)-1-methyl-2-oxoethyl]amino}ethyl]-N'-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]isophthalamide Authors: Munshi, S. Deposit date: 2007-08-16 Release date: 2008-04-22 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.8 Å) Cite: BACE-1 inhibition by a series of psi[CH2NH] reduced amide isosteres Bioorg.Med.Chem.Lett., 16, 2006
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2007-08-16
