Structure of HDAC6 zinc-finger ubiquitin binding domain in complex with SGC-UBD253 chemical probe
收藏Protein Data Bank Japan2023-08-16 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8g45
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Structure of HDAC6 zinc-finger ubiquitin binding domain in complex with SGC-UBD253 chemical probe Descriptor: 3-[8-chloro-3-(2-{[(2-methoxyphenyl)methyl]amino}-2-oxoethyl)-4-oxo-3,4-dihydroquinazolin-2-yl]propanoic acid, Histone deacetylase 6, ZINC ION Authors: Harding, R.J, Franzoni, I, Mann, M.K, Szewczyk, M, Mirabi, B, Owens, D.D.G, Ackloo, S, Scheremetjew, A, Juarez-Ornelas, K.A, Sanichar, R, Baker, R.J, Dank, C, Brown, P.J, Barsyte-Lovejoy, D, Santhakumar, V, Schapira, M, Lautens, M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) Deposit date: 2023-02-08 Release date: 2023-05-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6. J.Med.Chem., 66, 2023
创建时间：
2023-02-08
