Survival and virulence of Candida auris under selected environmental stress

This dataset presents the results of the evaluation of the potential of Candida auris strains to survive selected environmental stress. Cells of Candida auris strains were exposed to selected environmental stress including environmental UV and low cycling temperature regimes in simulated environments and their survival was quantified by estimating the viability of exposed cells at intervals. The impact of exposure to environmental stress on the virulence of C. auris cells was also evaluated based on their virulence in Galleria mellonella larvae. The impact of pre-exposure to clinical and environmentally relevant temperatures on the susceptibility of C. auris strains to medical and agricultural azoles was also evaluated.

The work was supported by the Natural Environment Research Council (Grant NE/V005847/1)