Phosphorylation of cPLA2 by ERK-2

ERK2 phosphorylates cPLA2, increasing enzymatic activity. The site of cPLA2 phosphorylation by ERK2 is Ser-505, the major site of cPLA2 phosphorylation observed in phorbol ester-treated cells.ERK2磷酸化cPLA2，从而增强其酶促活性。ERK2对cPLA2进行磷酸化的位点为Ser-505，这是在佛波酯处理细胞中观察到的cPLA2磷酸化的主要位点。