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PICTographPlus: Data Sets and Resources

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NIAID Data Ecosystem2026-05-10 收录
下载链接:
https://data.mendeley.com/datasets/cv66sgfcfn
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资源简介:
All the code are freely available at https://github.com/KarchinLab/pictographPlus and https://github.com/KarchinLab/PICTographPlus_manuscript. Benchmarking dataset ------------------------------------------------------------------------------- all_cells_with_hmm.rds: inferCNV object containing copy number results cell_groups.rds: inferCNV cell grouping results tree.csv: copy number tree benchmarking_PICTographPlus_results.csv: collected results from benchmarking dataset using PICTographPlus benchmarking_baseline_results.csv: collected results from benchmarking dataset using the baseline analysis Case analysis dataset ------------------------------------------------------------------------------- gene_sets_extended.txt: gene sets used for GSEA analysis Inputs: CRUK0004_input: input data for TRACERx patient. CRUK0004_SNV.csv: input somatic mutation file CRUK0004_facets.csv: input somatic copy number file CRUK0004_RNA.csv: input RNA read counts MK74_input: input data for Semaan et al. IPMN patient. MK74_snv.csv: input somatic mutation file MK74_cn.csv: input somatic copy number file MK74_rna.csv: input RNA read counts PCSI0380_input: input data for PanCuRx PDAC patient. PCSI0380_snv.csv: input somatic mutation/copy number file PCSI0380_.csv: input RNA read counts Outputs: CRUK0004_output: output data for TRACERx patient. MK74_output: output data for Semaan et al. IPMN patient. PCSI0380_output: output data for PanCuRx PDAC patient. Each of the above output folder contains the following files: tree.csv: PICTographPlus tree subclone_proportion.csv: subclone proportion for each sample clusterAssign.csv: assignment of mutation to each cluster purity.csv: estimated purity per sample mcf.csv: cluster mutation cellular fraction clonal_expression.csv: clone-level gene expression GSEA: gene set enrichment analysis results
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2026-01-14
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