Forensic Low Pass Whole Genome Sequencing
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Democratizing investigative genetic genealogy PI: August Woerner ; University of North Texas Health Science Center NIJ Grant Manager: Tiffany Layne (Tiffany.Layne@usdoj.gov) Related URLs: https://github.com/Ahhgust/Tapir https://github.com/Menggg/kniLP Study Summary: We evaluated the feasibility of using low pass whole genome sequencing to evaluate identity and relatedness. The study was conducted on reference profiles, in vitro heat-treated samples, as well as cadeveric samples. Included are assessments of genotype imputation, as well as maximum likelihood techniques, to genotype challenged samples and then infer distant relatives in said samples. We provide key summary statistics on these studies, including genotype accuracy, call rate and various descriptors of sample throughput. Award # 15PNIJ-23-GG-04213-DNAX Data Collection Time Period: 2023-2025
