Additional file 1 of Mass spectrometry-based proteomics profiling of dogs with and without oral diseases: a systematic review

Supplementary Material 1: Supplementary Table 1: List of the most abundant proteins reported in the included studies. Green highlight represents the most abundant proteins found in healthy dogs; Orange highlight represents the most abundant proteins found in healthy dogs and dogs with periodontal diseases; Yellow highlight represents the most abundant proteins found in dogs with benign oral tumors; Light blue highlight represents the most abundant proteins found in dogs with early-stage oral melanoma; Purple highlight represents the most abundant proteins found in dogs with late-stage oral melanoma; Red highlight represents the most abundant proteins found in dogs with oral squamous cell carcinoma; Grey highlight represents the most abundant proteins found in dogs with periodontal diseases, benign oral tumors, early-stage oral melanoma; late-stage oral melanoma, and oral squamous cell carcinoma; Dark red highlight represents the most abundant proteins found in dogs with dental calculus; Light blue highlight represents the most abundant proteins found in dogs with mixed cancers; and Orange red highlight represents the most abundant proteins found in dogs with periodontal diseases.Supplementary Table 2: List of names of all breeds of dogs used in the included studies along with the number of dogs used. Supplementary Table 3: Gene Ontology analysis – biological processes of the most abundant proteins among healthy dogs identified in the included studies. Supplementary Table 4: Gene Ontology analysis – cellular compartments of the most abundant proteins among healthy dogs identified in the included studies.Supplementary Table 5: Gene Ontology analysis – molecular functions of the most abundant proteins among healthy dogs identified in the included studies. Supplementary Table 6: KEGG pathway analysis of the most abundant proteins among healthy dogs identified in the included studies. Supplementary Table 7: Gene Ontology analysis – biological processes of the most abundant proteins among periodontitis dogs identified in the included studies. Supplementary Table 8: Gene Ontology analysis – cellular compartments of the most abundant proteins among periodontitis dogs identified in the included studies. Supplementary Table 9: Gene Ontology analysis – molecular functions of the most abundant proteins among periodontitis dogs identified in the included studies. Supplementary Table 10: KEGG pathway analysis of the most abundant proteins among periodontitis dogs identified in the included studies. Supplementary Table 11: Gene Ontology analysis – biological processes of the most abundant proteins among dogs with calculus identified in the included studies. Supplementary Table 12: Gene Ontology analysis – cellular compartments of the most abundant proteins among dogs with calculus identified in the included studies.Supplementary Table 13: Gene Ontology analysis – molecular functions of the most abundant proteins among dogs with calculus identified in the included studies.Supplementary Table 14: KEGG pathway analysis of the most abundant proteins among dogs with calculus identified in the included studies.Supplementary Table 15: Gene Ontology analysis – biological processes of the most abundant proteins among dogs with oral tumors identified in the included studies.Supplementary Table 16: Gene Ontology analysis – cellular compartments of the most abundant proteins among dogs with oral tumors identified in the included studies.Supplementary Table 17: Gene Ontology analysis – molecular functions of the most abundant proteins among dogs with oral tumors identified in the included studies.Supplementary Table 18: Protein-Protein interactions analysis of the most abundant proteins among healthy dogs identified in the included studies. Supplementary Table 19: Protein-Protein interactions analysis of the most abundant proteins among dogs with calculus identified in the included studies. Supplementary Table 20: Protein-Protein interactions analysis of the most abundant proteins among periodontitis dogs identified in the included studies. Supplementary Table 21: Protein-Protein interactions analysis of the most abundant proteins among dogs with oral tumors identified in the included studies.