Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation

In this study, blood proteome characterization in face transplantation using longitudinal serum samples from six face transplant patients was carried out with SOMAscan platform. Overall, 24 serum samples from 13 no-rejection, 5 nonsevere rejection and 6 severe rejection episodes were analyzed.<br>Files attached:<br><b><i>HMS-16-007.20160218.adat</i></b>- raw SomaScan dataset presented in adat format.<b><i></i></b><br><b><i>HMS-16-007_SQS_20160218.pdf</i></b>- technical validation report on the dataset.<br><b><i>HMS-16-007.HybNorm.20160218.adat</i></b>- SomaScan dataset after hybridization control normalization presented in <i>adat </i>format.<b><i></i></b><br><b><i>HMS-16-007.HybNorm.MedNorm.20160218.adat</i></b>- SomaScan dataset after hybridization control normalization and median signal normalization presented in<i>adat </i>format.<b><i><br></i></b><b><i>HMS-16-007.HybNorm.MedNorm.Cal.20160218.adat</i></b>- SomaScan dataset after hybridization control normalization, median signal normalization, and calibration presented in <i>adat </i>format.<br><b><i>HMS-16-007.HybNorm.MedNorm.Cal.20160218.xls </i></b><i>- </i>SomaScan dataset after hybridization control normalization, median signal normalization, and calibration presented in Microsoft Excel Spreadsheet format.<b><br></b><b><i>Patients_metadata.txt</i> </b>– metadata file containing patients’ demographic and clinical information presented in tab-delimited text format. Metadata is linked to records in the SomaScan dataset via ‘SampleType’ column.<b></b><b><i><br></i></b><b><i>SciData_R_script.R</i></b>– this script is given as an example of a downstream statistical analysis of the HMS-16-007.HybNorm.MedNorm.Cal.20160218.adat dataset.<br><br><b><i>SciData_R_script_SessionInfo</i></b> - Session information for SciData_R_script.R script.<br><br><br>