Additional file 1 of A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial–mesenchymal transition via the canonical Wnt/β-catenin signaling pathway
To elucidate the mechanism of ALDH18A1-driven gastric carcinogenesis and identify its downstream transcriptional targets, we conducted genome-wide RNA sequencing in HGC-27 cells knockdowning ALDH18A1,
Additional file 13. Dataset S6. FASTA file containing the sequences of the receptors used for the CLANS and phylogenetic tree shown in Additional file 3: Fig. S3 and Fig. 3, respectively.
We have found several genetic changes in the TGF-beta-type II receptor gene in human gastric cancer cell lines resistant to the growth inhibitory effect of TGF-beta. Southern blot analysis showed dele
The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,