Differential Lysotracker Uptake Defines Two Populations of Distal Epithelial Cells in Idiopathic Pulmonary Fibrosis

For this project alveolar epithelial type-II cells (AT-II) were FACS sorted from 8 donor lungs and 6 fibrotic lungs. The main goals of this experiment is to identify differences in transcriptional programms in AT-II cells from human donor and IPF patients. A total of 14 independent samples (8 from donor lungs, 6 from IPF lungs) were hybridized on Agilent Whole-transcriptome arrays.