Complete Dataset for "Microbiome-Directed Therapies Enhance the SCFA–Treg–Barrier Axis in Rheumatoid Arthritis: A Systematic Review"

This dataset contains the supplementary materials for the systematic review titled "Microbiome-Directed Therapies Enhance the SCFA–Treg–Barrier Axis in Rheumatoid Arthritis: A Systematic Review" It includes comprehensive study characteristics for 80 included studies (59 preclinical, 21 human), risk-of-bias assessments (RoB 2 and SYRCLE), full search syntaxes updated to 05 February 2026, and the PRISMA 2020 compliance checklist. The dataset includes: manuscript Figure 1 PRISMA Figure Figure 2 Mechanistic schematic of the SCFA–Treg–barrier axis Supplementary Table S1: Characteristics of all 80 included studies (59 preclinical, 21 human) Supplementary Table S2: Risk-of-bias assessments (Cochrane RoB 2 for RCTs; SYRCLE for preclinical) Supplementary Table S3: Complete list of 260 studies excluded at full-text with reasons Supplementary Table S4: Full electronic search strategies for PubMed, Embase, Cochrane CENTRAL Supplementary Table S5: Data extraction forms and verification records Supplementary Table S6 PRISMA 2020 flow diagram and compliance checklist