Flutamide treated rat hepatocytes in microfluidic biochips. Rattus norvegicus

We investigated the effects of the flutamide (FLU) -induced liver injury in primary rat hepatocytes using our liver microfluidic biochips. Flutamide is used a non-steroidal anti-androgenic drug. Two flutamide concentrations, 10µM and 100µM, were used to expose the hepatocytes for 24h under perfusion. Overall design: Primary rat hepatocytes were cultivated in microfluidic biochips and treated with 10 and 100µM of flutamide for 24h