Crystal structure of the catalytic domain of c-Met kinase in complex with ARQ 197
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Crystal structure of the catalytic domain of c-Met kinase in complex with ARQ 197 Descriptor: 1-[(3R,4R)-4-(1H-indol-3-yl)-2,5-dioxopyrrolidin-3-yl]pyrrolo[3,2,1-ij]quinolinium, Hepatocyte growth factor receptor Authors: Eathiraj, S, Palma, R, Volckova, E, Hirschi, M, France, D.S, Ashwell, M.A, Chan, T.C. Deposit date: 2011-04-11 Release date: 2011-04-27 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-Met) protein autophosphorylation by ARQ 197. J.Biol.Chem., 286, 2011
创建时间：
2011-04-11
