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Assessing the role of NLRX1 during mucosal immune responses to H. pylori in mice

NIAID Data Ecosystem2026-05-10 收录

黏膜免疫调节

幽门螺杆菌感染模型

数据链接：

https://immport.org/shared/study/SDY579 数据链接链接失效反馈

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资源简介：

This study examines the role of NLRX1 in modulating immune responses to H. pylori infection.

应用场景：

创建时间：

2025-10-30

幽门螺杆菌感染模型

胃肠道疾病机制

Humans infected with Helicobacter pylori have abnormally low levels of the antioxidant vitamin C, which protects against the formation of carcinogenic nitrosamines, in gastric juice. Guinea pigs, like

PubMed Central50

Formulation, High Throughput In Vitro Screening and In Vivo Functional Characterization of Nanoemulsion-Based Intranasal Vaccine Adjuvants

鼻内疫苗佐剂

黏膜免疫调节

Vaccine adjuvants have been reported to induce both mucosal and systemic immunity when applied to mucosal surfaces and this dual response appears important for protection against certain pathogens. De

NIAID Data Ecosystem40

SCID/NCr Mice Naturally Infected with Helicobacter hepaticus Develop Progressive Hepatitis, Proliferative Typhlitis, and Colitis

幽门螺杆菌感染模型

免疫病理学

Hepatitis, proliferative typhlitis, and colitis were characterized in young adult and older SCID/NCr mice naturally infected with Helicobacter hepaticus. Liver lesions consisted of Kupffer, Ito, and o

PubMed Central30

Commensal induced intraepithelial lymphocytes regulate intestinal epithelial cells turnover

黏膜免疫调节

肠道上皮稳态

role of MHCII expression in intestinal immunity

NIAID Data Ecosystem40

HP45

幽门螺杆菌感染模型

细菌趋化性突变体

Eight to thirteen-weeks-old wild-type and LysMcre mice were infected with two doses (days 0 and 2) of 5x10e7 CFU of either H. pylori strain SS1 or mutant ChePep resuspended in 1X PBS. An uninfected gr

NIAID Data Ecosystem40

Assessing the role of NLRX1 during mucosal immune responses to H. pylori in mice

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