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ACOT8-mediated palmitate accumulation promotes M1 macrophage polarization in renal ischemia–reperfusion injury via activation of the cGAS–STING pathway

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Figshare2026-03-11 更新2026-04-28 收录
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The precise etiology, intrinsic mechanisms, and effective interventions of renal ischemia-reperfusion injury are not sufficiently understood.To investigate the molecular basis, we carried out single-cell RNA sequencing using two distinct mouse models: Sham and IRI.

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2026-03-11
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