Cell adhesion force microscopy
收藏PubMed Central1999-01-19 更新2026-04-25 收录
下载链接：
https://pmc.ncbi.nlm.nih.gov/articles/PMC15160/
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资源简介：
The adhesion forces of cervical carcinoma cells in tissue culture were measured by using the manipulation force microscope, a novel atomic force microscope. The forces were studied as a function of time and temperature for cells cultured on hydrophilic and hydrophobic polystyrene substrates with preadsorbed proteins. The cells attached faster and stronger at 37°C than at 23°C and better on hydrophilic than on hydrophobic substrates, even though proteins adsorb much better to the hydrophobic substrates. Because cell adhesion serves to control several stages in the cell cycle, we anticipate that the manipulation force microscope can help clarify some cell-adhesion related issues.
提供机构：
National Academy of Sciences
创建时间：
1999-01-19
