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Intestinal iron transporters are essential for manganese absorption and excess in SLC30A10 deficiency

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP507916
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资源简介:
SLC30A10 deficiency is an inherited disease characterized by manganese excess, neurological dysfunction, liver disease, and polycythemia. It is due to loss of SLC30A10-mediated manganese excretion via the gastrointestinal tract. In this study, we investigate the role of intestinal iron transporters Dmt1 and ferroportin in absorption of manganese in Slc30a10-deficient mice.
创建时间:
2024-05-18
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